Author

Victor D. Varner

The University of Texas at DallasORCID 0000-0002-4575-4733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adil R. KhaniD· 2 shared Jacopo FerruzziiD· 2 shared Afeefah Khazi-SyediD· 1 shared Andrew R. JamiesoniD· 1 shared Angela Fan· 1 shared Austin Mills· 1 shared Chengsong ZhuiD· 1 shared Cheryl M. LewisiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

Adil R. KhanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer

Nicole C. Huning, Munir H. Buhaya, Victor Nguyen, Afeefah Khazi-Syed, Haider Ali, Adil R. Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, , Jacopo Ferruzzi

This study identifies biomechanical stiffening and fibrotic remodeling as hallmarks of early-onset colorectal cancer, showing their role in tumor initiation.

Advanced Science · Dec 1, 2025Peer-reviewedBioengineering

Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress

Mitzy A. Cowdin, Tuli Pramanik, Shelby R. Mohr-Allen, Yuting Fu, Austin Mills, Stephen B. Spurgin, Victor D. Varner, George E. Davis, Ondine B. Cleaver

This paper shows that Lats1/2 are essential for vascular remodeling and response to shear stress in embryonic endothelial cells, leading to vascular defects and embryonic lethality.

Arteriosclerosis Thrombosis and Vascular Biology · Jun 12, 2025Peer-reviewedDevelopmental Biology

Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung

Kara E. Peak, Poornacharanya Rajaguru, Adil R. Khan, Jason P. Gleghorn, Girgis Obaid, Jacopo Ferruzzi, Victor D. Varner

The paper uses photocrosslinking to alter tissue stiffness in embryonic lungs and shows it inhibits epithelial budding morphogenesis.

bioRxiv · Aug 22, 2024 · PreprintBioengineering