Author

Zaverio M. Ruggeri

Scripps Research InstituteORCID 0000-0003-0807-1295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro Zarpellon· 1 shared Antonella Zampolli· 1 shared Eric Won· 1 shared Jennifer Nagrampa Orje· 1 shared Roberto AiolfiiD· 1 shared Sachiko KanajiiD· 1 shared Taisuke KanajiiD· 1 shared Yosuke MorodomiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPhysiology

Alessandro Zarpellon

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1 paper

Recent·Most cited

Human PAR1 expressed on mouse platelets contributes to hemostasis and arterial occlusion

Sachiko Kanaji, Alessandro Zarpellon, Roberto Aiolfi, Yosuke Morodomi, Jennifer Nagrampa Orje, Antonella Zampolli, Eric Won, Zaverio M. Ruggeri, Taisuke Kanaji

This paper demonstrates that human PAR1 expressed in mouse platelets affects hemostasis and arterial occlusion, with vorapaxar reversing these effects.

bioRxiv · Jun 3, 2025 · PreprintPhysiology