Developmental BiologyOncogenePeer-reviewed
Phosphatidylinositol-3 kinase activity controls survival and stemness of zebrafish hematopoietic stem/progenitor cells
Sasja Blokzijl-Franke, Bas Ponsioen, Stefan Schulte‐Merker…·Jeroen den Hertog
The paper investigates how PI3K signaling affects survival and stemness of zebrafish HSPCs during EHT, finding that both loss of Pten and PI3K inhibition induce apoptosis, while surviving cells show reduced stemness.
7 citations