Author

Lauren A. Cowley

University of BathORCID 0000-0003-0835-7971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Organism:rat· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alanna CallendrelloiD· 1 shared Carolina Ferrari· 1 shared Crista B. WadsworthiD· 1 shared Cristina MerlaiD· 1 shared David M. AanenseniD· 1 shared Davide SasseraiD· 1 shared Derek R. MacFaddeniD· 1 shared Edward J. FeiliD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alanna CallendrelloORCID

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2 papers

Recent·Most cited

Convergence and global epidemiology of Klebsiella pneumoniae plasmids harbouring the iuc3 virulence locus.

Marjorie J. Gibbon, Natacha Couto, Keira Cozens, Samia Habib, Lauren A. Cowley, David M. Aanensen, Jukka Corander, Harry A. Thorpe, Marit Andrea Klokkhammer Hetland, Davide Sassera, Cristina Merla, Marta Corbella, Carolina Ferrari, Katy Turner, Kwanrawee Sirikancha, , Edward J. Feil

The paper characterizes iuc3-carrying plasmids in Klebsiella pneumoniae isolates, identifying convergent plasmids with resistance and virulence genes and highlighting their global epidemiology.

bioRxiv · Jan 5, 2024 · PreprintGenomics

Rapid heuristic inference of antibiotic resistance and susceptibility by genomic neighbor typing

Karel Břinda, Alanna Callendrello, Kevin C. Ma, Derek R. MacFadden, Themoula Charalampous, Robyn S Lee, Lauren A. Cowley, Crista B. Wadsworth, Yonatan H. Grad, Grégory Kucherov, Justin O’Grady, Michael Baym, William Paul Hanage

This paper introduces a method to rapidly infer antibiotic resistance and susceptibility from bacterial genomes using genomic neighbor typing, achieving high sensitivity and specificity within minutes to hours.

Nature Microbiology · Feb 10, 2020Peer-reviewedBioinformatics