Davide Sassera

SYMBIO-SCAN identifies high-quality full-length 16S rRNA gene sequences from long reads to discover bacterial symbionts in beetles, revealing novel genera and species.

The paper identifies an introgressed galectin-like protein in Cryptosporidium parvum anthroponosum as a potential driver of its human tropism through interaction with the human insulin-degrading enzyme.

This paper introduces a method to recover Borrelia genomes from ticks using Whole Genome Amplification, significantly reducing the time and effort compared to traditional culturing methods.

This study investigates the translocation of Pseudomonas aeruginosa between body sites in hospitalized patients, finding that clones often move from the respiratory tract to the gut.

This study sequenced tick-associated Francisella endosymbionts and analyzed their genomes to understand metabolic pathways and biogeographic patterns.

The paper characterizes a persistent, azole-resistant C. parapsilosis strain responsible for a hospital outbreak, identifying genetic mutations linked to antifungal resistance.

This paper reclassifies SHV β-lactamase alleles in K. pneumoniae genomes based on mutations, improving genotype-phenotype understanding and updating the Kleborate tool.

The paper uses whole genome sequencing to identify three distinct populations of Cryptosporidium parvum, showing the emergence and spread of a European population to the USA.

This paper optimizes machine learning prediction of MICs in Klebsiella pneumoniae by evaluating regression vs classification approaches based on antibiotic concentration levels.

The paper introduces a novel index, FOGS, to measure bacterial genome plasticity by incorporating time and gene transfer events, showing higher FOGS in high-risk clones.

The paper characterizes iuc3-carrying plasmids in Klebsiella pneumoniae isolates, identifying convergent plasmids with resistance and virulence genes and highlighting their global epidemiology.

The paper evaluates reducing AlphaFold-Multimer model sampling for faster protein-protein interaction predictions without compromising accuracy.

The paper reports the genome sequence of a novel Coxiella endosymbiont from the tick Amblyomma nuttalli, revealing convergent genome reduction across Coxiella clades.

The paper tracks the emergence and global spread of 7 SARS-CoV-2 amino acid variants, identifying 6 phylogenetic clades with changing frequencies over time.