Yoshihiko Umesono

Duplicated shh genes in Xenopus laevis reveal an essential role in early limb development

This study shows that shh.L is essential for initial limb outgrowth in Xenopus laevis, revealing conserved SHH dependence for early appendage initiation across vertebrates.

The CoP Assay: A Robust Method for Quantitative Assessment of Food Intake in the Planarian Dugesia japonica

The paper introduces the CoP assay to quantify food intake in planarians, showing they regulate consumption based on diet quality and exhibit satiety after partial ingestion.

Step-by-step protocol for making a knock-in Xenopus laevis to visualize endogenous gene expression

The paper describes a CRISPR-Cas9-based knock-in protocol in Xenopus laevis to visualize endogenous gene expression using reporter genes.

Proliferation maintains the undifferentiated status of stem cells: the role of the planarian cell cycle regulator Cdh1

The paper shows that cell cycle arrest is necessary for stem cell differentiation in planarians, as inhibiting Cdh1 disrupts tissue homeostasis and regeneration.