Sacri R. Ferrón

This study shows neural stem cells can maintain function outside their normal anatomical niche, revealing plasticity in stem-cell environment relationships.

This study shows TET2 regulates 5hmC deposition in adult neural stem cells, balancing stemness and differentiation through distinct epigenetic programs.

The paper shows that TET3 protects the Dlk1-Dio3 imprinted locus from hypomethylation during iPSC reprogramming from neural stem cells.

The paper analyzes genomic imprinting changes during reprogramming of adult neural stem cells into iPSCs, identifying transcriptome and methylation alterations linked to pluripotency and epigenetic quality.

This study shows p27 represses SOX2 and its downstream targets to regulate cell cycle exit in adult neurogenesis and oligodendrogenesis.

The paper shows that IGF2 promotes differentiation of adult NSCs by inducing Cdkn1c expression, which drives cell cycle exit and terminal differentiation into astrocytes, neurons, and oligodendrocytes.