Bioengineered human tonsil organoids as an immuno-engineering platform for evaluating immune functions
Intan Rosalina Suhito, Donovan Eu, Hong Sheng Cheng, Nguan Soon Tan, Zhe Zhang Ryan Lew, Kai Sen Tan, Justin Jang Hann Chu, Giselle G. K. Ng, Yanfang Su, Gavin J. D. Smith, Chee Wah Tan, Andy Kah Ping Tay
The paper develops bioengineered human tonsil organoids (BTOs) to study immune functions, showing they support antigen-specific responses and immune-stromal interactions comparable to native tissues.
bioRxiv · Oct 4, 2025 · PreprintBioengineering