Gavin J. D. Smith

The paper develops an integration-free CRISPR platform to study host dependencies of respiratory viruses in human nasal epithelium, showing ACE2 and TMPRSS2 are critical for SARS-CoV-2 and hCoV-NL63 infection.

The paper identifies novel SARS-CoV-2-related viruses in Cambodian bats, revealing genetic diversity and potential zoonotic risk through receptor-binding domain analysis and pseudovirus assays.

This study shows genetic introgression promotes diversification in Old World fruit bats by enabling trait sharing and hybrid speciation, with evidence from genomic analysis of 93 Cynopterus individuals.

This study shows that HA deletions and substitutions in influenza B/Victoria viruses enhance replication and virulence, contributing to their evolutionary success and vaccine challenges.

The paper develops bioengineered human tonsil organoids (BTOs) to study immune functions, showing they support antigen-specific responses and immune-stromal interactions comparable to native tissues.

This study assesses the seroprevalence of influenza A and B viruses in goats and sheep, finding high antibody rates against avian H5, H7, and H9 subtypes, suggesting these animals may be novel hosts for pandemic influenza viruses.

The paper introduces a logistic regression pipeline for classifying genetic sequences, achieving high accuracy even with degraded data and identifying clade-defining mutations.