Maruan Hijazi

This study shows lung cancer stem cells adapt to the brain microenvironment through neuro-mimetic reprogramming and epigenetic changes, enabling metastasis.

The paper applies community detection to kinase networks derived from phosphoproteomics data to identify new signaling pathway components, finding TTK as a potential member of PI3K/AKT/mTOR signaling.

The paper predicts human kinase-kinase regulatory relationships and their effects using data-driven methods, revealing a sparse but denser network than typically considered.