Dan Zhang

This paper develops eTd-mtABEs, engineered mitochondrial A-to-G base editors with enhanced efficiency and targeting scope, enabling efficient generation of mtDNA disease models in rat embryos.

The paper presents a chromosome-scale reference genome of tea tree using SMRT sequencing and Hi-C, enabling annotation of gene families and retrotransposon diversity.

This study de novo assembles and annotates the chloroplast and mitochondrial genomes of Camellia sinensis var. assamica, revealing structural and functional features of these genomes.