Molecular BiologyCellPeer-reviewed
XIST ribonucleoproteins promote female sex-biased autoimmunity
Diana R. Dou, Yanding Zhao, Julia A. Belk…·Howard Y. Chang
This study shows that Xist ribonucleoprotein complexes drive sex-biased autoimmunity in males, leading to autoimmune pathology and reprogramming of immune cells to resemble female patterns.