Author

Anton Wutz

ETH ZurichORCID 0000-0002-4377-6330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 4 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Eishi AizawaiD· 3 shared Giulio Di MininiD· 3 shared Charles-Étienne DumeauiD· 2 shared Remo FreimanniD· 2 shared Allan FengiD· 1 shared Ami A. ShahiD· 1 shared Antoine H.F.M. PetersiD· 1 shared Bingfei YuiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersDevelopmental Biology

Eishi AizawaORCID

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5 papers

Recent·Most cited

The scramblases VMP1 and TMEM41b are required for primitive endoderm specification by targeting WNT signaling

Markus Holzner, Tea Sonicki, Hugo Hunn, Federico Uliana, Weijun Jiang, Vamshidhar R. Gade, Karsten Weis, Anton Wutz, Giulio Di Minin

This study shows that VMP1 and TMEM41b are required for primitive endoderm specification by regulating WNT signaling in mouse ESCs.

Cell Death and Differentiation · Dec 18, 2024Peer-reviewedDevelopmental Biology

XIST ribonucleoproteins promote female sex-biased autoimmunity

Diana R. Dou, Yanding Zhao, Julia A. Belk, Yang Zhao, Kerriann M. Casey, Derek C. Chen, Rui Li, Bingfei Yu, Suhas Srinivasan, Brian T. Abe, Katerina Kraft, Cecilia Hellström, Ronald Sjöberg, Sarah Esther Chang, Allan Feng, , Howard Y. Chang

This study shows that Xist ribonucleoprotein complexes drive sex-biased autoimmunity in males, leading to autoimmune pathology and reprogramming of immune cells to resemble female patterns.

Cell · Feb 1, 2024Peer-reviewedMolecular Biology

Comprehensive comparison of female germ cell development in vitro and in vivo identifies epigenetic gene regulation crucial for oocyte development and embryonic competence

Eishi Aizawa, Evgeniy A. Ozonov, Yumiko Kawamura, Charles-Étienne Dumeau, So I Nagaoka, Tomoya S. Kitajima, Mitinori Saitou, Antoine H.F.M. Peters, Anton Wutz

The EMBO Journal · Oct 18, 2023Peer-reviewedDevelopmental Biology

Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome

Eishi Aizawa, Corinne Kaufmann, Sarah Sting, Sarah Boigner, Remo Freimann, Giulio Di Minin, Anton Wutz

The paper describes a method to generate haploid primordial germ cell-like cells from haploid mouse ESCs and shows Xist activation from a single X chromosome.

Stem Cell Reports · Dec 16, 2021Peer-reviewedDevelopmental Biology

Polyploidy of semi-cloned embryos generated from parthenogenetic haploid embryonic stem cells

Eishi Aizawa, Charles-Étienne Dumeau, Remo Freimann, Giulio Di Minin, Anton Wutz

This study generates fertile semi-cloned mice using parthenogenetic haploid embryonic stem cells with deleted DMRs, revealing frequent polyploidy in resulting embryos.

PLoS ONE · Sep 10, 2020Peer-reviewedDevelopmental Biology