Polybasic patches in both C2 domains of Synaptotagmin-1 are required for evoked neurotransmitter release
Zhenyong Wu, Lu Ma, Nicholas A. Courtney, Jie Zhu, Yongli Zhang, Edwin R. Chapman, Erdem Karatekin
This study shows that polybasic patches in both C2A and C2B domains of Synaptotagmin-1 are required for evoked neurotransmitter release, but not for spontaneous release or the readily releasable vesicle pool.
bioRxiv · Jul 5, 2021 · PreprintNeuroscience