Cancer BiologybioRxivPreprint
LSD1 inhibition corrects dysregulated MHC-I and dendritic cells activation through IFNγ-CXCL9-CXCR3 axis to promote antitumor immunity in HNSCC
Amit Kumar Chakraborty, Lina Kroehling, Rajnikant Dilip Raut…·Manish V. Bais
This study shows LSD1 inhibition enhances antitumor immunity in HNSCC by upregulating MHC-I and activating the IFNγ-CXCL9-CXCR3 axis through dendritic cells and CD8+ T cells.
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