Author

Gunhild Layer

University of FreiburgORCID 0000-0003-0974-173XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Agnes BartelsiD· 1 shared Emely JockmanniD· 1 shared Federica FrascognaiD· 1 shared Göksu Oral· 1 shared Hannah Herrmann· 1 shared Jennifer N. AndexeriD· 1 shared Katrin Zoller· 1 shared Lars-Hendrik KoeppliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Agnes BartelsORCID

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2 papers

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedAug 6, 2026

Evolutionary insights into bilin biosynthesis: Functional characterization of pre-PcyA enzymes

Federica Frascogna, Nathan C. Rockwell, Gunhild Layer, Nicole Frankenberg‐Dinkel

This study characterizes pre-PcyA enzymes, showing they evolved into FDBRs with distinct bilin biosynthesis capabilities, revealing their catalytic plasticity and evolutionary divergence.

DOI 10.1002/pro.70748

bacteria (other)proteomics

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BiochemistryChemBioChemPeer-reviewedJul 26, 2026

S-Adenosyl-D-methionine as a Non-Physiological Substrate for a Wide Range of SAM-Dependent Enzymes

Philipp Germer, Lukas Gericke, Lars-Hendrik Koeppl…·Jennifer N. Andexer

This study investigates the ability of SAM-dependent enzymes to accept D-SAM instead of L-SAM, finding that several enzymes can utilize D-SAM and highlighting implications for enzyme engineering.

1 citation

experimental assay

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