Evgeniy A. Khrapov

This paper introduces a method combining exome sequencing and chromosome conformation capture to detect both SNVs and SVs, demonstrating its effectiveness in identifying causative variants in rare disorders.

This paper introduces an S1 nuclease-based Hi-C method for chromatin conformation capture, offering improved chromatin fragmentation and library preparation compared to DNase I Hi-C.

The paper analyzes BRCA1 and BRCA2 mutations in ovarian cancer patients from Russia, identifying common and novel variants and estimating the age of a founder mutation.

NGS-PrimerPlex designs primers for multiplex PCR to create NGS panels, achieving high coverage in sequencing the LRRK2 gene.

This study creates chimeric reverse transcriptases by fusing M-MuLV RT with DNA-binding domains, improving processivity and inhibitor resistance.