Atsuo Kikuchi

This paper develops a dried blood spot proteomics method to diagnose citrin deficiency by quantifying SLC25A13 and identifying a 15-protein signature with high accuracy.

This study compares drug metabolic capacity and cytotoxicity of Caco-2 cells, cryopreserved enterocytes, and stem cell-derived intestinal epithelial cells to identify a better model for drug discovery.

The paper develops resources for NGS analysis using the Japanese reference genome JG, including variant calling, annotation, and coordinate conversion tools.

This paper constructs and integrates three de novo Japanese human genome assemblies to create a population-specific reference, improving variant calling accuracy for Japanese individuals.