Systems BiologybioRxivPreprint
A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts
Karl Kumbier, Maike A. Roth, Zizheng Li…·Steven J. Altschuler
The paper develops a scalable platform combining microscopy and machine learning to subtype ALS patient fibroblasts, identifying a FUS-ALS phenotypic score that correlates with age and treatment response.