Stefan Lutz

This paper introduces DA-MEK, a high-throughput platform for enzyme variant screening and kinetic analysis using droplet arrays, demonstrating accurate and efficient measurement of catalytic efficiencies.

This paper evolves a terminal deoxynucleotidyl transferase for enzymatic DNA synthesis using modified substrates, showing improved activity, template promiscuity, and thermostability.

This paper describes an engineered T7 RNA polymerase, T7-68, that improves mRNA synthesis by efficiently co-transcriptional capping and reducing dsRNA byproducts.