Author

Gerhard A. Burger

Leiden UniversityORCID 0000-0003-1062-5576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Joost B. BeltmaniD· 3 shared Bob van de WateriD· 2 shared Sylvia E. Le DévédeciD· 2 shared Carlijn M. LemsiD· 1 shared Daphne NesenberendiD· 1 shared Sander C. HilleiD· 1 shared Steven WinkiD· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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3 shared papersSystems Biology

Joost B. BeltmanORCID

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3 papers

Recent·Most cited

Systems BiologyRoyal Society Open SciencePeer-reviewedNov 1, 2022

Bidirectional crosstalk between epithelial-mesenchymal plasticity and IFNγ-induced PD-L1 expression promotes tumor progression

Gerhard A. Burger, Daphne Nesenberend, Carlijn M. Lems…·Joost B. Beltman

The paper develops a mathematical model showing bidirectional crosstalk between EMT and IFNγ-induced PD-L1 expression, revealing how they influence tumor progression and immunotherapy resistance.

11 citations

statistical model

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BioinformaticsbioRxivPreprintOct 6, 2022

User-friendly high-content imaging analysis on a single desktop: R package H5CellProfiler

Steven Wink, Gerhard A. Burger, Sylvia E. Le Dévédec…·Bob van de Water

H5CellProfiler is an R package that enables user-friendly analysis of large single-cell datasets on a local desktop with efficient memory usage and track labeling.

3 citations

imagingstatistical model

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Systems BiologyFrontiers in Cell and Developmental BiologyPeer-reviewedApr 25, 2022

Density-dependent migration characteristics of cancer cells driven by pseudopod coordination

Gerhard A. Burger, Bob van de Water, Sylvia E. Le Dévédec, Joost B. Beltman

This study investigates how cancer cell density affects migration speed and persistence in TNBC cells using experimental data and computational modeling.

16 citations

humanimaging

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