Bram Burger

This study extends protein interaction networks by incorporating small molecules, protein isoforms, and post-translational modifications to better represent biological systems.

PathwayMatcher maps omics data to pathway networks considering protein isoforms and modifications, enabling more precise pathway analysis.

This study examines the structure of pathway knowledgebases like Reactome and its impact on interpreting biomedical datasets, aiming to improve user understanding and result reliability.