Author

Melanie Weber

Harvard UniversityORCID 0000-0003-1104-7181Unclaimed ORCID profile · follow to get notified of new preprints

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Melanie Weber1 paper

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Research Focus:clustering· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

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Hattie ChungiD· 1 shared Louis BoucherieiD· 1 shared Nithya BhaskeriD· 1 shared Stefanie SpeideliD· 1 shared Vladislav KimiD· 1 shared

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BioinformaticsbioRxivPreprintAug 22, 2025

Contrastive Poincare Maps: uncovering developmental lineages from single-cell data with scalable hyperbolic embeddings

Nithya Bhasker, Hattie Chung, Louis Boucherie…·Melanie Weber

This paper introduces Contrastive Poincare Maps (CPM) for embedding developmental scRNA-seq data in hyperbolic space, achieving better hierarchy preservation and scalability than existing methods.

DOI 10.1101/2025.08.22.671789

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