Author

Yuanzhe Su

Northwestern UniversityORCID 0000-0003-1110-2822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Luay Matthew AlmassalhaiD· 2 shared Nicolas AcostaiD· 2 shared Ruyi GongiD· 2 shared Vadim BackmaniD· 2 shared Andrew D. StephensiD· 1 shared Emily M. Pujadas-LiwagiD· 1 shared Geng WangiD· 1 shared Jane FrederickiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Luay Matthew AlmassalhaORCID

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2 papers

Recent·Most cited

BioengineeringLight Science & ApplicationsPeer-reviewedMar 16, 2025

Three-color single-molecule localization microscopy in chromatin

Nicolas Acosta, Ruyi Gong, Yuanzhe Su…·Vadim Backman

This paper develops a three-color single-molecule localization microscopy protocol to study chromatin structure, revealing that heterochromatin and euchromatin are not distinct territories but are spatially coupled.

14 citationstop 4%

humanfluorescence / live-cell microscopy

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BioengineeringJournal of Cell SciencePeer-reviewedJan 29, 2025

Nuclear blebs are associated with destabilized chromatin packing domains

Emily M. Pujadas-Liwag, Nicolas Acosta, Luay Matthew Almassalha…·Vadim Backman

The paper investigates how nuclear blebs alter chromatin packing domains, finding fragmentation of nanoscopic heterochromatin domains within blebs.

16 citations

humanimaging

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