Author

Han Xue

Shanghai Jiao Tong UniversityORCID 0000-0003-1137-2873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Alden Yen-Wen Huang· 1 shared Annelise Yoo Mah-SomiD· 1 shared Annick Raas‐RothschildiD· 1 shared Boris KereniD· 1 shared Carrie Costin· 1 shared Chi YangiD· 1 shared Christina G.S. PalmeriD· 1 shared Cyril MignotiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Alden Yen-Wen Huang

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 20, 2026

Histone H2BK120 ubiquitination modulates PRC1 activity and H2AK119ub deposition on nucleosomes

Ying Yu, Dan Cai, Yuzhu Zhang…·Jing Huang

The paper reveals how H2BK120ub enhances PRC1 activity and modulates H2AK119ub deposition, linking active and repressive histone modifications in gene regulation.

DOI 10.64898/2026.02.20.706939

mouseChIP-seq

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GeneticsbioRxivPreprintFeb 6, 2024

Loss of function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly

Yue Huang, Kristy L. Jay, Alden Yen-Wen Huang…·Julián A. Martínez-Agosto

The paper identifies de novo RBBP5 variants in individuals with neurodevelopmental disorders and shows they cause loss of function through structural and Drosophila model analyses.

2 citations

Drosophilaexperimental assay

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