Ana Carolina Ramos Guimarães

This paper introduces a benchmark dataset for enzyme function prediction and shows that current models struggle to distinguish non-functional enzyme variants from functional ones.

This study evaluates the effectiveness of antimalarials administered via tarsal contact to block Plasmodium vivax transmission by Anopheles darlingi mosquitoes.

GAPO uses genetic algorithms with protein language models and force fields to optimize protein sequences, outperforming simulated annealing in binding and stability.