Sexual Dimorphism of Cancer-Associated Fibroblasts Governs Matrix and Vascular Organisation in Breast Cancer
Peng Liu, Fiona R. Saunders, Matthew Everest, Natthaya Eiamampai, Matthew P. Humphries, Camilla Coulson‐Gilmer, Giulia Conti, Lucy F. Stead, Rasha Abu Eid, Valerie Speirs
This study shows that male and female cancer-associated fibroblasts in breast cancer have distinct transcriptional programs and functional behaviors affecting matrix and vascular organization.
bioRxiv · Aug 28, 2026 · PreprintCancer Biology