Martijn F. L. Derks

The paper develops BovCADD, a cattle-specific deleteriousness score for substitutions, and shows it can distinguish pathogenic variants from background variation across the genome.

This paper estimates variant intolerance scores for cattle genes and predicts protein domains, finding similar patterns to other species and moderate correlation with human orthologs.

The paper presents CattleGTEx, a resource characterizing regulatory effects in cattle, resolving GWAS signals and providing insights into adaptive evolution and selection.

The paper introduces a pipeline for generating CADD scores across species, presenting updated chickenCADD and newly generated turkeyCADD scores.

The paper assembles a gap-free telomere-to-telomere pig genome, revealing new genes, structural variations, and insights into centromere evolution and breed-specific selection.

The paper analyzes unmapped reads from whole-genome sequencing data of cattle breeds to reveal geographic variation in pathogen diversity across Europe and Africa.

This paper models DNA methylation networks during pig fetal development using a joint fused ridge approach, revealing key roles for fetal-maternal immunity and the circulatory system.

The paper describes the European Reference Genome Atlas (ERGA) pilot project, which tests a decentralized model for producing high-quality reference genomes across 98 European species.

The paper identifies rare deleterious recessive variants in pigs using a large-scale sequence-based GWAS, revealing significant QTLs for growth rate and backfat thickness.

The paper presents a high-quality chromosome-level turkey genome assembly using long-read technologies and Hi-C data, revealing structural variations and a large inversion on the Z chromosome.