Lipid moieties of sonic hedgehog are important for interaction with its inhibitor, WIF1
Krisztina Kerekes, Mária Trexler, László Bányai, László Patthy
The paper shows that lipid modifications on sonic hedgehog (Shh) enhance its binding to WIF1, an inhibitor, suggesting lipid moieties are critical for their interaction.
bioRxiv · Feb 23, 2026 · PreprintBiochemistry