BiophysicseLifePeer-reviewed
Active regulation of the epidermal growth factor receptor by the membrane bilayer
Shwetha Srinivasan, Xingcheng Lin, Xuyan Chen…·Gabriela S. Schlau‐Cohen
This study shows that the lipid composition of the membrane actively regulates EGFR conformation and signaling, independent of ligand binding, with implications for cancer and normal cell function.