Author

Roel M. Schaaper

National Institutes of HealthORCID 0000-0003-1344-3196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam BurkholderiD· 1 shared Niketa BhawsinghkaiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperGenetics

Adam BurkholderORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintOct 21, 2022

Detection of DNA replication errors and 8-oxo-dGTP-mediated mutations in E. coli by Duplex DNA Sequencing

Niketa Bhawsinghka, Adam Burkholder, Roel M. Schaaper

This study uses Duplex Sequencing to detect DNA replication errors and mutations in E. coli, identifying in vivo mutations in mutL and mutT strains and revealing context effects and strand bias.

DOI 10.1101/2022.10.21.513255

E. coliwhole-genome sequencing

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