Chao Ma

The China Brain Multi-omics Atlas Project (CBMAP) creates a comprehensive molecular reference map of over 1,000 human brains to address underrepresentation in East Asian populations and advance research on aging and neuropsychiatric disorders.

This study identifies population-specific eQTLs in brain tissues from European, African American, and Asian ancestry individuals, revealing new schizophrenia risk genes and variants missed in European-only datasets.

This study shows that neuronal C-reactive protein activates FcγRI signaling in DRG neurons, contributing to neuropathic pain, and that disrupting this pathway reduces pain in a rat model.

The paper creates a proteomic map of the human cerebral cortex by analyzing 29 Brodmann areas, identifying cluster-specific and BA-specific proteins and their functional associations.

This study creates a single-cell transcriptome atlas of human and macaque retinas across ages, revealing species-specific molecular features and age-related changes in cell types and disease associations.