MicrobiologybioRxivPreprint
Minimum inoculum of resistance assay for evaluating for anti-toxoplasmosis compounds that target phenyl alanine tRNA synthetase
Taher Uddin, Payal Mittal, Han Xie…·L. David Sibley
The paper develops a Minimum Inoculum for Resistance (MIR) assay to evaluate anti-Toxoplasma gondii compounds, showing that inhibitors of phenylalanine tRNA synthetase require higher parasite inocula to induce resistance compared to DNA synthesis inhibitors.
DOI 10.64898/2026.03.02.709153