Rebecca Weinberg

This paper develops a spatio-temporal analysis framework to uncover coupled mutagenic mechanisms in radiation-induced genomic instability using whole-genome sequencing data from irradiated human cells.

The paper models how low-dose radiation affects nuclear morphology by linking RNA-seq data to cell-painting imaging features over time using an interpretable inverse modeling framework.

The paper introduces SCALE, a pipeline for longitudinal cell painting analysis, demonstrating its ability to handle imaging variability and enable consistent comparisons across time points.