Author

Yu Xi

Brookhaven National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Abi Osborn· 1 shared Andrew Phillip WestiD· 1 shared Byung-Jun YooniD· 1 shared Carl Wei-Chan TongiD· 1 shared Changhao Li· 1 shared Guang ZhaoiD· 1 shared Jacob KuempeliD· 1 shared Jiaying ZhuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPathology

Abi Osborn

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Author profile →

2 papers

Recent·Most cited

METTL14-dependent m6A modification restrains interferon signaling to prevent myocarditis and dilated Cardiomyopathy

Yu Xi, Jacob Kuempel, Sukwon Choi, Patrick S DeSpain, Tianru Zhang, Jiaying Zhu, Abi Osborn, Reed A Rivera, Songxiao Zhong, Xiaoyang Wu, Yong-Xiao Wang, Zhenyu Li, Andrew Phillip West, Changhao Li, Carl Wei-Chan Tong, , Xu Peng

This study shows that METTL14-dependent m6A modification prevents myocarditis and dilated cardiomyopathy by restraining IFN signaling and necroptosis in cardiomyocytes.

bioRxiv · Apr 6, 2026 · PreprintPathology

An Integrated and Configurable End-to-End Pipeline for Longitudinal Cell Painting Analysis

Guang Zhao, Yu Xi, Mikhail Titov, Rebecca Weinberg, Sara Forrester, Tom Brettin, Shinjae Yoo, Xiaoning Qian, Byung-Jun Yoon

The paper introduces SCALE, a pipeline for longitudinal cell painting analysis, demonstrating its ability to handle imaging variability and enable consistent comparisons across time points.

bioRxiv · Feb 23, 2026 · PreprintBioinformatics