Author
Icahn School of Medicine at Mount SinaiORCID 0000-0003-1412-543XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Mohsin M. Naqvi, Maria Zacharopoulou, Satyaki Saha…·Laura S. Itzhaki
The paper investigates how two small molecule activators of PP2A, ATUX-8385 and DBK-776, affect the structural stability of the PR65 scaffold using biophysical and computational methods.
Sema Zeynep Yilmaz, Anupam Banerjee, Satyaki Saha…·Mert Gür
The paper investigates how SMAPs bind to PR65, showing that S2 is a stable binding site while S1 is not, and that binding promotes an extended PR65 conformation favorable for PP2A holoenzyme assembly.
Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin…·Ricky W. Johnstone
The paper identifies a PP2A-Integrator complex that opposes CDK9 activity to regulate transcription and shows its therapeutic synergy in leukemia.