Dylan Novack

The paper uses computational and experimental methods to identify transition intermediates in the μ-opioid receptor-Gi protein complex that encode ligand efficacy.

This paper elucidates the mechanistic basis for the selective recognition of FcγRIIa by monoclonal antibody IV.3 through a combination of experimental and computational methods.

This study uses free energy calculations to predict affinity maturation of miniproteins, finding that simulation methods can classify mutations but are less accurate than Flex ddG Rosetta.