Author

Clara Lopes Novo

Babraham InstituteORCID 0000-0003-1435-4136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Andrea F. Lopez‐ClavijoiD· 1 shared Bebiana C. SousaiD· 1 shared Bryony J. LeekeiD· 1 shared Chetan PoudeliD· 1 shared Colin HockingsiD· 1 shared David BarnedaiD· 1 shared Donja Karimlou· 1 shared Eleanor SheekeyiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Andrea F. Lopez‐ClavijoORCID

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2 papers

Recent·Most cited

Developmental BiologyCell ReportsPeer-reviewedDec 1, 2025

The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity.

Roshni A. de Souza, David Barneda, Donja Karimlou…·Véronique Azuara

The paper identifies a lipid metabolism-induced checkpoint during the exit of naïve pluripotency that ensures genome integrity through telomere regulation.

DOI 10.1016/j.celrep.2025.116654

mousebulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedJun 20, 2022

Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells

Clara Lopes Novo, Emily V. Wong, Colin Hockings…·Peter J. Rugg‐Gunn

This study shows that satellite repeat transcripts in mouse ESCs drive heterochromatin condensates, which are crucial for chromosome stability and nuclear organization.

62 citationstop 4%

mousebulk RNA-seq

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