Author

Sumitha Rajendrarao

Scripps Research InstituteORCID 0000-0003-1449-1720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Manish SharmaiD· 1 shared Neelam ShahaniiD· 1 shared Srinivasa SubramaniamiD· 1 shared Uri Nimrod Ramírez-JarquíniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Manish SharmaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJan 8, 2020

cGAS, a DNA Sensor, Promotes Inflammatory Responses in Huntington Disease

Manish Sharma, Sumitha Rajendrarao, Neelam Shahani…·Srinivasa Subramaniam

This study identifies cGAS as a key DNA sensor upregulated in Huntington disease, promoting inflammation and autophagy through increased mRNA occupancy and protein activity.

2 citations

humanmouse

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