Hepatocyte androgen receptor in females mediates androgen-induced hepatocellular glucose mishandling and systemic insulin resistance
Stanley Andrisse, Mingxiao Feng, Zhiqiang Wang, Olubusayo Awe, Lexiang Yu, Haiying Zhang, Sheng Bi, Hongbing Wang, Linhao Li, Serene Joseph, Nicola M. Heller, Franck Mauvais‐Jarvis, Guang William Wong, James H. Segars, Andrew Wolfe, , Sheng Wu
This study shows that deleting the hepatic androgen receptor in female mice prevents androgen-induced insulin resistance and glucose intolerance.
bioRxiv · Jun 9, 2021 · PreprintMolecular Biology