Bin Tean Teh

The paper identifies heritable telomere variant sequences that determine allele-specific telomere length and shows their role in telomere maintenance and inheritance.

This paper investigates how whole-genome duplication affects biosynthetic gene clusters in Strychnos species, showing that pathway function can persist despite fragmentation and regulatory rewiring.

This study identifies transcriptomic and immune features of gastric cancer peritoneal metastases, highlighting predictive markers and therapeutic targets in the tumor microenvironment.

This study shows that family history collection improves the detection of pathogenic variants in genomic data, enhancing precision medicine by identifying high-risk individuals.

The paper identifies hundreds of genes deregulated by SVs in cancer, showing increased expression linked to SV breakpoints and enhancer elements.

The paper identifies recurrent PD-L1 structural rearrangements and JAK3 mutations in NKTL patients achieving CR with PD-1 blockade therapy, suggesting genomic screening may improve patient selection.

The paper develops a continuous gene expression score (CLEAR) for clear cell renal cell carcinoma that outperforms discrete subtypes in prognostic accuracy and treatment outcome correlation.