Developmental BiologybioRxivPreprint
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-PRC1 axis
Dahai Wang, Mayuri Tanaka-Yano, Eleanor Meader…·R. Grant Rowe
The paper identifies a Lin28b-let-7-PRC1 axis that regulates hematopoietic maturation across development, with Cbx2 playing a key role in controlling developmental timing of hematopoietic transcription factors.
DOI 10.1101/2022.01.05.474696