Cancer BiologyCancer ResearchPeer-reviewed
Adaptive regulation of dNTP homeostasis confers osimertinib resistance in EGFR mutant non-small cell lung carcinoma
Qian Xie, Yingying Wang, Anthony Fernandez…·Min Li
This study identifies dNTP homeostasis regulation as a mechanism of osimertinib resistance in EGFR-mutant NSCLC, revealing therapeutic targets through two regulatory axes.
DOI 10.1158/0008-5472.can-25-3237