NeurosciencebioRxivPreprint
Early peripheral immune signaling precedes tau elevation and blood-brain barrier disruption in Alzheimer's disease
Aaron Burberry, Penelope H. Benchek, Mark J. Lowe…·Jagan A. Pillai
DOI 10.64898/2026.04.02.716122
Author
Broad InstituteORCID 0000-0003-1552-8695Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Aaron Burberry, Penelope H. Benchek, Mark J. Lowe…·Jagan A. Pillai
Francesco Limone, Daniel A. Mordes, Alexander Couto…·Kevin C. Eggan
The paper identifies cell type-specific molecular changes in ALS patients, showing enrichment of genetic risk factors in extratelencephalic neurons and altered responses in oligodendrocytes and microglia.