Alissa C. Bleem

This study compares two arabinose utilization pathways in Pseudomonas putida to optimize muconic acid production from lignocellulosic sugars, finding a tradeoff between growth rate and yield.

This paper improves muconic acid production in Pseudomonas putida by overcoming PCA and catechol accumulation through adaptive evolution and metabolic engineering, showing that increased CatA1 expression enhances pathway efficiency.

The paper tests how environmental conditions affect the fitness of microbial consortia with different metabolite exchange strategies, finding that a lactic acid-exchanging consortium outperformed wild type under weakly buffered conditions but not under highly buffered conditions.