Nucleotide and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA
Shivansh Mahajan, Ashley E. Pall, Yancheng E. Li, Timothy L. Stemmler, Douglas C. Rees, William Clemons
This study reports cryo-EM structures of ArsA, an ATPase involved in arsenite efflux, showing conformational changes driven by nucleotides and AsIII binding.
Proceedings of the National Academy of Sciences · Aug 29, 2025Peer-reviewedBiochemistry