Author

Jiaxin Fan

University of PennsylvaniaORCID 0000-0003-1590-9850Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jiaxin Fan1 paper · Nanjing University

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:deconvolution· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mingyao LiiD· 3 shared Rui XiaoiD· 3 shared Xuran WangiD· 2 shared Chenyi XueiD· 1 shared Hanrui ZhangiD· 1 shared Jian HuiD· 1 shared Muredach P. ReillyiD· 1 shared Qihuang ZhangiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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3 shared papersGenomics

Mingyao LiORCID

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3 papers

Recent·Most cited

GenomicsBriefings in BioinformaticsPeer-reviewedSep 15, 2022

MuSiC2: cell type deconvolution for multi-condition bulk RNA-seq data

Jiaxin Fan, Yafei Lyu, Qihuang Zhang…·Rui Xiao

MuSiC2 improves cell type proportion estimation in bulk RNA-seq data from different clinical conditions using an iterative method, outperforming traditional approaches.

74 citationstop 3%

humanbulk RNA-seq

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BioinformaticsPLoS GeneticsPeer-reviewedMar 4, 2021

Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data

Jiaxin Fan, Xuran Wang, Rui Xiao, Mingyao Li

This paper introduces BSCET, a method that detects cell-type-specific allelic expression imbalance using bulk RNA-seq data integrated with scRNA-seq-derived cell-type information, identifying genes related to type 2 diabetes progression.

27 citations

humanbulk RNA-seq

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GenomicsbioRxivPreprintOct 8, 2019

ASEP: gene-based detection of allele-specific expression in a population by RNA-seq

Jiaxin Fan, Jian Hu, Chenyi Xue…·Mingyao Li

ASEP detects gene-level allele-specific expression in populations using RNA-seq, identifying differential ASE between conditions and extending findings to cardiometabolic traits.

DOI 10.1101/798124

humanbulk RNA-seq

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