BiochemistrybioRxivPreprint
Structural and cellular insights into the inhibition of the drug efflux activity of the HEDGEHOG receptor PATCHED1
Oussama Houha, Maryem Wachich, Claire Debarnot…·Valérie Biou
The paper investigates the structure of PTCH1 bound to the inhibitor PAH, revealing its mechanism of blocking drug efflux and providing insights for drug design.
DOI 10.64898/2026.03.23.713596