Author

Thomas C. Thannickal

University of California SystemORCID 0000-0003-1623-9545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Jerome M. SiegeliD· 2 shared Ming‐Fung Wu· 2 shared Marcia E. Cornford· 1 shared Ronald McGregoriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersNeuroscience

Jerome M. SiegelORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 12, 2025

Brainstem pathology in human narcolepsy: Neurodegeneration in the locus coeruleus in narcoleptic humans, but not in genetically narcoleptic mice or dogs

Thomas C. Thannickal, Ming‐Fung Wu, Marcia E. Cornford, Jerome M. Siegel

DOI 10.1101/2025.04.12.648456

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 22, 2023

Opiate anticipation,opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt receptor antagonist suvorexant, while opiate analgesia is maintained

Ronald McGregor, Ming‐Fung Wu, Thomas C. Thannickal, Jerome M. Siegel

This study shows that suvorexant blocks morphine-induced changes in Hcrt neurons, microglial activation, and anticipatory behavior but preserves morphine analgesia.

7 citations

humanexperimental assay

𝕏 PostBluesky