Sean B. Ostlund

The paper shows that the dorsomedial prefrontal cortex (dmPFC) uses reward predictions to regulate how rewards are pursued, with cues signaling imminent reward suppressing instrumental seeking and cues signaling sparse reward invigorating it.

The paper investigates how dopamine release in the nucleus accumbens core is shaped by reward prediction and influences reward-pursuit strategies in rats.

This study examines how acute and prolonged morphine withdrawal affects motivation and goal-directed behavior in rats, finding distinct impacts on reward processing and flexibility.

This study examines how repeated THC exposure during adolescence or adulthood affects reward learning and motivated behavior in rats, finding age-dependent changes in cognitive and motivational processes.

This study investigates the role of mesolimbic dopamine projections in cue-motivated reward seeking versus retrieval, finding that dopamine inhibition disrupts seeking but not retrieval.

This study shows that NAc cholinergic interneurons inhibit cue-motivated behavior in rats through acetylcholine release and nicotinic receptor activation.